NeurIPS 2022 · Datasets & Benchmarks

A large-scale dataset for automatic differential diagnosis

1.3M synthetic patients, 49 pathologies, and 223 binary/categorical/multi-choice evidences — built to train and evaluate models that ask questions and reason over differential diagnoses, not just predict a single label.

Explore a sample patient Read the paper Download (figshare)
Overview diagram of the DDXPlus dataset generation and structure

Why DDXPlus

What sets it apart from single-label symptom-checker datasets.

A full differential, not one label

Each patient carries a ranked, probabilistic set of plausible pathologies — how clinicians actually reason.

Structured, hierarchical evidence

223 binary, categorical, and multi-choice evidences with built-in dependencies, enabling realistic sequential-questioning agents.

Severity & demographics

Pathologies carry clinical severity; patients span age, sex, and region — for studying triage and fairness.

Dataset at a glance

~1.3M patients split into train/validate/test, generated from 49 pathologies and 223 evidences.

Pathology distribution
Age & sex distribution
Conversation length & ground-truth rank

Explore a sample

Patient

Data


      

Consultation

Differential diagnosis

What a model must reason over for this patient — not just the single confirmed pathology above.

Data schema

The three JSON/CSV structures behind DDXPlus, with a real excerpt from the released English dataset for each — documented in full in the README.


      

Access & quickstart

Grab the released files and load a split in a few lines of pandas.

Download

  • Englishrecommended figshare →

    Same data and format as the French release, but with English names/codes throughout.

  • Frenchoriginal figshare →

    The version all results in the NeurIPS 2022 paper were obtained on.

  • release_evidences.json — all 223 evidences
  • release_conditions.json — all 49 pathologies
  • release_train_patients.zip — training split
  • release_validate_patients.zip — validation split
  • release_test_patients.zip — test split

Released under a CC-BY licence.

Quickstart

Python

      

Field reference for every column above: Data schema.

As seen in

Papers and benchmarks built on DDXPlus.

Cite this dataset

If you use DDXPlus in your work, please cite the NeurIPS 2022 paper.

BibTeX